Directional characteristics of action potential propagation in cardiac muscle. A model study.
نویسندگان
چکیده
منابع مشابه
Directional characteristics of action potential propagation in cardiac muscle. A model study.
Propagation of an elliptic excitation wave front was studied in a two-dimensional model of a thin sheet of cardiac muscle. The sheet model of 2.5 x 10 mm consisted of a set of 100 parallel cables coupled through a regular array of identical transverse resistors. The membrane dynamics was represented by a modified Beeler-Reuter model. We defined the charging factor (CF) to represent by a single ...
متن کاملAction potential propagation in a thick strand of cardiac muscle.
A theoretical model of action potential propagation in a thick strand of cardiac muscle is presented. The calculation takes into account the anisotropic and syncytial properties of the tissue, the presence of the interstitial space, the effect of the surrounding tissue bath, and the variation of the potential both along the strand length and across the strand cross section. The bidomain model i...
متن کاملThe Different Mechanisms of Action Potential Propagation in the Heart
It was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. Some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (AP). It seems that some other types of mechanisms must be involved in AP propagation. In this article, we...
متن کاملThe Different Mechanisms of Action Potential Propagation in the Heart
It was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. Some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (AP). It seems that some other types of mechanisms must be involved in AP propagation. In this article, we...
متن کاملNonuniform muscle fiber orientation causes spiral wave drift in a finite element model of cardiac action potential propagation.
INTRODUCTION Reentrant tachyarrhythmias are thought to involve spiral waves of excitation and recovery that may be nonstationary. The effect of muscle fiber curvature on spiral and planar wave propagation was studied using a computational model. METHODS AND RESULTS Two-dimensional anisotropic cardiac propagation was modeled using a finite element method to solve a modification of the FitzHugh...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1991
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.69.2.378